This study of androgenic alopecia patients reports that stress was associated with AGA in both men and women, with notable findings differing by gender, age, and AGA type.
January 2009 in “대한피부과학회지” In this study, researchers found that stress is linked to androgenic alopecia in both male and female patients, with an increasing number of female patients in their forties experiencing the condition.
January 2008 in “대한피부과학회지” This study found that among Korean patients with androgenetic alopecia, a significant portion had a family history, and pelvic ultrasound showed increased rates of abnormalities in female patients, although not recommended as a routine test.
January 2008 in “대한피부과학회지” This study found that androgenetic alopecia in Koreans is associated with family history and increased androgen levels, with Norwood class IIIv most common in males and Ludwig class I in females.
September 2004 in “Experimental Dermatology” This study reports that stress-related neurohormones and factors, such as CRH and SP, can inhibit hair growth and alter immune functions in murine and human hair follicles.
34 citations
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January 2005 in “Journal of the American Veterinary Medical Association” This study found that cyclosporine A treatment at 5 mg/kg/day may reduce inflammation and promote gland regeneration in dogs with sebaceous adenitis, though symptoms returned when treatment stopped.
24 citations
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September 2011 in “Autoimmunity” This review discusses the role of natural killer cells in the pathogenesis of blistering diseases and proposes further research on their interaction with the skin, reporting no new clinical results.
3 citations
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January 2025 in “动物学研究” This study used high-resolution imaging and genetic analysis to investigate hair density in the Dazu black goat, identifying key genes like GJA1 and GPRC5D involved in follicle development and maintenance, and highlighted their role in animal hair density regulation.
1 citations
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March 2024 in “Skin research and technology” In this study, a modified Xception deep learning model achieved a 92% accuracy rate in diagnosing hair and scalp disorders, significantly outperforming other models, suggesting AI could improve dermatological diagnostics' accuracy and accessibility.
1 citations
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May 2015 in “Dermatologic Therapy” The microstrip technique for hair transplantation is effective and discreet for patients needing fewer than 1500 grafts.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers observed that alopecia areata patients showed higher Th1 and Th2 responses against specific melanogenesis-related protein epitopes, suggesting a role in disease activity and potential targets for diagnostics and therapies.
13 citations
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May 2014 in “PubMed” This study observed that class IV diffuse proliferative glomerulonephritis was the most common form of lupus nephritis among the children studied, with remission achieved in a significant portion after treatment.
209 citations
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March 1998 in “Biochemical and biophysical research communications” This study identified a novel class of nonsteroidal ligands that can mimic the effects of dihydrotestosterone on androgen receptors, suggesting potential therapeutic applications in male fertility and hormone replacement therapy.
5 citations
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February 2014 in “Journal of chemical ecology” This study determined the broad class and molecular species of glycerophospholipids in Eastern red bat sebum, highlighting differences from previous bat lung surfactant studies.
4 citations
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November 2004 in “Clinical and Experimental Dermatology” This study identified a new class of shed hair in young women that could impact future hair research and suggests that the concept of hair miniaturization in androgenetic alopecia may need revision.
20 citations
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December 2010 in “Journal of Morphology” In this study, researchers found that alpha-keratin homologs similar to those in mammalian hair are present in the claws of the lizard Anolis carolinensis, suggesting a structural role during claw formation.
2 citations
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November 2008 This article discusses the implementation of problem-based learning in a ninth-grade biology class in Singapore, highlighting the use of authentic, student-driven inquiries to explore topics like nutrition and health without reporting new empirical results.
9 citations
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February 1984 in “Zentralblatt für Veterinärmedizin Reihe A” This study found that feeding piglets high levels of egg white led to severe biotin deficiency, causing hair loss and brittle claws, highlighting biotin's role in maintaining healthy skin and claws.
26 citations
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March 2014 in “Rheumatology” This study confirms an association between TNF-α antagonist exposure and alopecia, indicating a class effect among the medications examined.
3 citations
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October 2019 in “EMBO molecular medicine” This study reports that the nuclear receptor co-repressor 1 (NCoR1) inhibits cardiac hypertrophy by stabilizing the MEF2 and class II HDACs complex, potentially offering a target for new therapies.
3 citations
,
June 1993 in “Hair transplant forum international” This abstract reports on a presentation at a meeting that detailed the hair restoration of a patient with Norwood Class 5 pattern using 1,325 four-haired minigrafts, but it provides no clinical results.
131 citations
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March 2004 in “The American journal of pathology” This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
14 citations
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February 2014 in “Experimental Cell Research” This review examines the role of stem cells and their niches in continuously growing ectodermal organs like teeth, hair, and claws, providing insights from mouse models without presenting new research findings.
8 citations
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September 1981 in “Zentralblatt für Veterinärmedizin Reihe A” In this animal study, pigs on a biotin-deficient diet showed significant hair loss, weak and brittle claws, and skin lesions after 8–10 weeks, with tissue necrosis observed microscopically after 15 weeks.
December 2024 in “Genome Biology and Evolution” This study found that the Florida worm lizard has lost certain genes associated with claw development, which are present in other lizard species with claws, suggesting a link between the evolution of their limbless body and the loss of claw-related genes.
61 citations
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June 2022 in “IEEE Journal of Biomedical and Health Informatics” This study introduced a novel deep clustering approach for melanoma detection from dermoscopic images, demonstrating improved performance over existing methods by mitigating class imbalance issues using a center-oriented margin-free triplet loss.
17 citations
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January 2015 in “Dermatology online journal” This report describes a patient experiencing hair repigmentation linked to adalimumab therapy, a TNF inhibitor, a phenomenon not previously associated with this class of drugs.
8 citations
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May 2025 in “Pharmaceuticals” This article reviews 27 small-molecule drugs approved by the FDA in 2024, noting that among them, eight "first-in-class" drugs with breakthrough therapy status show distinct mechanisms and substantial efficacy improvements in various conditions like cancer and chronic diseases.
4 citations
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June 2025 in “MedComm” This review detailed the significant progress and challenges in the design and application of PROTACs, a novel class of cancer therapeutics, highlighting their clinical trials, design complexities, and the role of artificial intelligence in improving their efficacy and selectivity for cancer therapy.
4 citations
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January 2011 This thesis explores the synthesis and antiproliferative properties of phenylpropanoid sucrose esters, noting the absence of synthetic methods for most of this compound class due to their structural complexity.