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Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Nerves are crucial for the regeneration of various body parts in many animals.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Sebocytes play a key role in controlling androgen levels in human skin.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

New effective scar treatments are urgently needed due to the current options' limited success.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Hair loss needs more research for better treatments.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.