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This study found that dutasteride affected spinal bone formation in curdlan-treated SKG mice, while DHT treatment reduced osteoblast differentiation in vitro, suggesting that DHT inhibition might unexpectedly increase spinal ankylosis progression in ankylosing spondylitis patients.

This study found that para-phenylenediamine induces cytotoxic effects in normal human hair dermal papilla cells by altering microRNA expression and causing cell death, cell cycle arrest, and oxidative stress.

This consensus from the Taiwanese Dermatological Association suggests that for mild to moderate alopecia areata, first-line treatments may include topical or intralesional corticosteroids, possibly with topical minoxidil, while severe cases might require systemic corticosteroids or Janus kinase inhibitors.

This article discusses the dermatologic impacts of gender-affirming medical care in transgender adolescents and emphasizes the importance of patient-centered care to improve dermatologic and overall outcomes; it reports no new clinical results.

This review examines the effects of sex hormones on hair growth and the pathogenesis of related hair disorders, highlighting current management benefits and controversies but reporting no new results.

This review of female androgenetic alopecia treatments reports limited therapeutic options due to unclear pathogenesis, with minoxidil as the only FDA-approved treatment and adjuvant therapies under investigation.

This review explores current and emerging treatments for polycystic ovary syndrome, focusing on managing hyperandrogenism and cardiometabolic risk, but reports no new clinical results.

In this study, germ-free male mice showed altered levels of certain neuroactive steroids in the brain and periphery, suggesting microbiota may influence neuroendocrine pathways that support brain functioning.

This study reported that dutasteride, identified through a drug repurposing strategy, showed the potential to reduce neuroinflammation and cognitive impairment in LPS-stimulated models.

This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.

This review discusses factors affecting hair health, types of alopecia, and the potential of phytochemicals in managing hair loss but reports no new clinical results; it highlights the need for further studies.

This review assesses the potential of dutasteride as a promising treatment for ALS due to its reported neuroprotective, antioxidant, and anti-inflammatory effects, but emphasizes that clinical studies are needed for confirmation.

This study suggests that a supercritical CO2 extract from wild-strawberry-processing waste may be an innovative and sustainable ingredient for cosmetic applications, particularly in treating androgenic-related skin conditions.

This literature review on androgenetic alopecia highlights its significant impact on patients' mental health and quality of life and discusses various treatment pathways, including topical, systemic, and surgical interventions, while emphasizing the need for continued research to develop effective therapies.

This study found that DNA methylation may regulate the differential expression of the BMP7 gene in Hu sheep lamb skin of different patterns, and it influences the proliferation and cell cycle of dermal papilla cells, with demethylation treatment increasing BMP7 expression and cell proliferation.

This review outlines the functional anatomy, pathology, and molecular mechanisms of androgenetic alopecia, emphasizing the need for multi-omics approaches to better understand this condition's biology.

This study evaluated compounds from Jatropha cordata bark, finding that a sterol mixture and n-heptyl ferulate demonstrated notable anti-inflammatory activity in murine macrophage cells without toxicity, suggesting potential for treating chronic inflammation.

This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.

This study found that Keratin 26 is expressed differently in hair follicle phases, particularly during catagen and telogen, influencing cashmere growth and interacting antagonistically with the BMP signaling pathway.

This case report documents a 59-year-old man in Taiwan who developed breast cancer while undergoing finasteride therapy for benign prostate hyperplasia, marking a rare side effect.

This study found that 12.5% moringa seed oil demonstrated optimal anti-alopecia activity in rabbits, significantly improving hair weight compared to the treatment with 0.1% finasteride.

In this study of 50 rural children with tinea capitis, 64% had the non-inflammatory type, while 28% had the inflammatory type, with most cases showing positive results in KOH examinations.

This study observed that certain herbal extracts may promote hair growth and inhibit hair loss in cell lines by affecting specific protein expressions similarly to minoxidil.

This study found that men aged 50 and older with clinical benign prostatic hyperplasia have a significantly higher prevalence of metabolic syndrome than those without the condition in the UK primary care population.

This review highlights that while dandruff affects over 50% of humans and cannot be fully eradicated, it can be controlled through chemical treatments that may cause side effects or herbal remedies such as Neem and Tea tree oil, which have longstanding use in hair care.

In this study, clobetasol propionate 0.05% ointment was found to induce hair regrowth in 28.5% of patients with severe alopecia areata under occlusive conditions, though long-term benefit was limited to 17.8%.

This study found that the prevalence of PCOS in Thai adolescents was 5.29%, with moderate acne identified as the strongest associated risk factor.

This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.

In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.

This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.