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New treatments for male hypogonadism are effective and should be personalized.

This review discusses the complex relationship between melasma and factors like female sex hormones, genetics, and ultraviolet light exposure, but reports no new clinical findings.

This review highlights the potential therapeutic applications of nandrolone, an anabolic steroid, for male health, but notes that more human studies are needed due to limited existing literature.

This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.

This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.

This review discusses the role of estrogen deficiency in post-menopausal skin aging and wound healing, highlighting opportunities for developing estrogen receptor-targeted therapies and reports no new clinical results.

This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.

This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.

In this study, women with idiopathic hirsutism who took finasteride for 9 months experienced a significant reduction in hirsutism scores compared to those receiving a placebo, with minimal side effects.

This review discusses hormone replacement therapy for women with premature ovarian insufficiency, strongly recommending it for symptom relief and bone protection, but notes a lack of evidence on optimal types and doses.

This review discusses how androgens may regulate wound healing and inflammation, noting that testosterone appears to inhibit healing and promote inflammation, but it reports no new clinical results.

This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

This review examines androgen replacement therapy in women for treating androgen deficiency symptoms and reports no new clinical results, while noting potential safety within a specific dose range.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Randomized trials reported that testosterone therapy improved sexual function in postmenopausal women with hypoactive sexual desire disorder, particularly those who had undergone oophorectomy, with reversible and well-tolerated side effects.

In this study, prolonged systemic administration of 17β-estradiol in castrated male mice delayed wound healing by inhibiting re-epithelialization and reducing collagen accumulation, with estrogen receptor-α likely mediating this effect.

This article states that hormone therapy with estrogens and antiandrogens for transgender females is within an obstetrician-gynecologist's practice scope and involves careful dosing and monitoring to manage short-term thrombotic risks.

This study found that in vitro treatments with 5alpha-reductase inhibitors and androgen receptor antagonists strongly stimulate VEGF expression in dermal papilla cells.

This study found that women with female pattern hair loss had increased 5α-reductase isozymes and decreased aromatase mRNA levels, potentially affecting their response to treatment.

This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.

This study describes a case where finasteride treatment for benign prostatic hypertrophy was associated with gynecomastia in a 62-year-old man, which resolved after the drug was discontinued.

This article reviews current evaluation and treatment options for androgenic alopecia in women and reports no new clinical results.

This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.

This study found that testosterone therapy can enhance sexual satisfaction and mood in surgically menopausal women on oestrogen, though ongoing monitoring and research are needed to assess long-term safety and effects in other groups.

This study found that testosterone replacement in castrated male rats counteracted endotoxemia-induced arterial baroreflex dysfunction without significantly affecting neuroinflammation.

This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

This article reviews the unapproved use of testosterone for treating female androgen insufficiency and reports no new clinical results.