research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
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research The Cascading Pathogenic Consequences of Sarcoptes Scabiei Infection That Manifest in Host Disease
Sarcoptes scabiei infection causes significant health and behavior changes in wombats.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Allopregnanolone Mediates the Exacerbation of Tourette-Like Responses by Acute Stress in Mouse Models
Stress worsens Tourette symptoms by increasing allopregnanolone levels.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid
High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
research Long Noncoding RNA and Gene Expression Analysis of Melatonin-Exposed Liaoning Cashmere Goat Fibroblasts Indicating Cashmere Growth
Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.
research Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride
Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
research The Pathophysiology of the Male Aging Face and Body
Aging in men is influenced by genetics and lifestyle, leading to muscle loss, bone issues, and skin damage.
research Association Between Serum Melatonin and Skin Aging in an Urban Population of Mongolia
Lower melatonin levels are linked to more skin aging.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.
research Photobiomodulation in Cells' Repair
Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research RSL4 Regulatory Network Acts as an Early Driver of Root Hair Growth at Low Temperature in Arabidopsis Thaliana
A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.
research Hair Cortisol: A Biomarker of Chronic Stress in Animals and Its Association With Reproduction
High levels of cortisol in hair show long-term stress which can lower fertility in animals.
research Study of Fecal Glucocorticoid Metabolite in Bears: A Review
Analyzing bear poop helps measure their stress without harming them.
research Development and Evaluation of Virgin Coconut Oil-Based Herbal Hair Tonic
The VCO-based herbal hair tonic is effective, safe for hair loss treatment, and can be mass-produced.
research Hair Regeneration by Small Molecules That Activate Autophagy
Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Screening for 21-Hydroxylase-Deficient Nonclassic Adrenal Hyperplasia Among Hyperandrogenic Women: A Prospective Study
Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Congenital Adrenal Hyperplasia: Current Insights in Pathophysiology, Diagnostics, and Management
Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research The Pathophysiology of Polycystic Ovary Syndrome: Understanding PCOS and Its Endocrinology
The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
research Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management
The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.