This study found that finasteride could enhance the stemness of dermal papilla cells, suggesting potential benefits for hair regeneration approaches.
660 citations
,
December 2011 in “Cell” This study found that distinct low-threshold mechanoreceptors innervate different hair follicle types in mice, suggesting that these follicles serve as unique mechanosensory structures in touch perception.
43 citations
,
December 2013 in “Stem Cells” Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.
41 citations
,
September 2014 in “Journal of Pharmacy and Pharmacology” This study found that melatonin significantly improved metabolic and reproductive parameters in PCOS-induced rats, with effects similar to metformin.
31 citations
,
May 2019 in “Nature communications” This study found that Blimp1+ cells from mice can generate sebaceous gland organoids in vitro, which mimic natural gland traits and may aid in studying acne vulgaris.
15 citations
,
June 2016 in “Computers in Biology and Medicine” This study's simulation found that Ascorbyl Tetraisopalmitate penetrates more efficiently through the skin's stratum corneum than via the infundibulum, following different pathways and dynamics in each membrane.
10 citations
,
November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
1 citations
,
August 2024 in “Heliyon” This study reports that hair follicle neural crest stem cells in mice can be differentiated into melanocytes, potentially aiding repigmentation in vitiligo-affected areas.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.
291 citations
,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
43 citations
,
September 2021 in “Nutrients” This review discusses the vast potential uses of persimmon beyond its dietary benefits, including applications in sustainability and new product development, but reports no new clinical outcomes.
38 citations
,
June 2018 in “Plant & cell physiology/Plant and cell physiology” This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.
9 citations
,
March 2022 in “Antioxidants” This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.
1 citations
,
August 2025 in “International Journal of Molecular Sciences” This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.
September 2026 in “Repository of the University of Ljubljana (University of Ljubljana)” This study analyzed hair styling mousses on the Slovenian market, finding that their formulations primarily rely on polymers, with no banned ingredients according to European cosmetics regulations.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this literature review, researchers explored the effectiveness, safety, and formulation challenges of herbal hair removal creams, focusing on medicinal plants like Cyperus rotundus and Aloe vera, and comparing their depilatory mechanisms to conventional chemical alternatives.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this literature review, researchers examined the effectiveness and safety of herbal hair removal creams, focusing on the pharmacological characteristics and depilatory activity of various medicinal plants, and compared their mechanisms to conventional chemical depilatories.
December 2025 in “Journal of the Bangladesh Agricultural University” This study documented 55 weed species at Daffodil International University, highlighting their ecological and cultural importance, with many species having recognized ethnobotanical uses such as hair growth and skin disorder treatments.
November 2020 in “Journal of The American Academy of Dermatology” This study investigated the use of spironolactone in patients with estrogen-dependent cancers, aiming to determine if it is linked to increased cancer recurrence risk, but results are not reported.
May 2020 in “Research, Society and Development” This study suggests that mutamba fruit, regardless of maturation stage, could be valuable in the food industry due to its high soluble solids, vitamin C, and mineral content.
204 citations
,
October 1999 in “EMBO journal” This study found that overexpression of activin in transgenic mice led to enhanced granulation tissue formation after skin injury due to changes in keratinocyte proliferation and differentiation.
77 citations
,
April 2009 in “British Journal of Dermatology” In this study, genetic variation in the CYP19A1 gene, particularly the common rs4646 C allele, was associated with an increased risk of female pattern hair loss, especially in women under 40.
72 citations
,
March 2013 in “Primates” In this study, the isotopic fractionation between tissues and diets of captive Japanese macaques was quantified, particularly noting hair's response to diet changes in controlled conditions, but these findings underscore the complexity of reconstructing long-term dietary history.
62 citations
,
April 2009 in “British Journal of Dermatology” This review discusses the potential markers for identifying and studying stem cells in the epidermis and hair follicles, highlighting their role in understanding skin disease pathogenesis and expanding therapeutic options, but reports no new findings.
38 citations
,
March 2010 in “Medicine” In this study, researchers found that hepatitis C virus infection is a significant risk factor for sporadic porphyria cutanea tarda, suggesting familial cases might be more prevalent in areas with low hepatitis C infection rates.
37 citations
,
January 2010 in “Acta dermato-venereologica” This study found that both men and women with androgenic alopecia had significantly higher triglycerides, total cholesterol, and LDL-C and lower HDL-C levels than controls, suggesting increased dyslipidemia prevalence.
24 citations
,
June 2021 in “Agronomy” This study found that biostimulant application in lettuce cultivation led to significant yield and phytochemical enhancements, with effects varying between green and red cultivars depending on the treatment method used.
22 citations
,
July 2019 in “PLOS ONE” This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.
16 citations
,
November 2020 in “PLOS ONE” This study found that lack of sleep, increased physical activity, and alopecia were associated with a higher risk of COVID-19 infection, while low-dose alcohol intake, hand hygiene, and daily fruit consumption were linked to reduced morbidity.
16 citations
,
November 2008 in “Journal of the American Academy of Dermatology” This case report describes a patient with a hepatitis C diagnosis whose acral rash, initially unresponsive to psoriasis treatment, showed significant improvement with oral zinc sulfate, suggesting a diagnosis of necrolytic acral erythema.