research Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice
Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.
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research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis
Mast cells and the CB1 receptor may be key in causing IgA vasculitis.
research A Review of the Evidence for and Against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
research Dermal Fibrosis in Male Pattern Hair Loss: A Suggestive Implication of Mast Cells
Mast cells might contribute to hair loss by causing skin thickening.
research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research A Nude Mouse Model of Hypertrophic Scar Shows Morphologic and Histologic Characteristics of Human Hypertrophic Scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research The Developing Immune Network in Human Prenatal Skin
Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
research Pathophysiology of the Burn Scar
Burn scars heal abnormally and more research is needed to find better treatments.
research Multiple Minute Digitate Hyperkeratosis
The document concludes that fexofenadine reduces inflammation in chronic hives, cholestyramine helps half of pregnant women with itchy rashes, and relaxing incisions are a good alternative in facial surgery for the elderly.
research Nuclear Factor (Erythroid-Derived 2)-Like-2 Pathway Modulates Substance P–Induced Human Mast Cell Activation and Degranulation in the Hair Follicle
Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
research Mast Cells and Scarring Alopecia: Is There a Clear Pathophysiological Relationship?
The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.
research Histidine Decarboxylase Expression Influences the Neofolliculogenesis of Newborn Mouse Dermal Cells
The gene HDC is important for the development of hair follicles in newborn mice.
research Cyclosporine-Induced Gingival Hyperplasia in a Patient With Lichen Planopilaris: Misfortunes Never Come Singly
A patient's gum problems worsened after using cyclosporine for a scalp condition, but improved with a lower dose.
research Randomized Split-Side Study Comparing Efficacy of Botulinum Toxin Type A Versus 0.9% Sodium Chloride in Scalp Psoriasis
Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
research General Dermatology: Comprehensive Overview of Dermatological Conditions
The document explains various skin conditions and their treatments.
research Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency
Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis
Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research Fascia Layer - A Novel Target for the Application of Biomaterials in Skin Wound Healing
The fascial layer is a promising new target for wound healing treatments using biomaterials.
research Clinicopathological Characteristics of Fibrosing Alopecia in a Pattern Distribution: A Single-Center, Retrospective Study
Younger people are at a higher risk for Fibrosing Alopecia in a Pattern Distribution than previously thought, with common symptoms and possible involvement of mast cells in its development.