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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Hyperprolactinemia should be treated before confirming a PCOS diagnosis.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Intradermal injections improve hair density and thickness better, while derma roller is more convenient.

A 70-year-old woman with a malignant adrenal tumor improved after surgery and radiotherapy.

Androgenetic alopecia is influenced by various factors and can be treated with medications, procedures, and non-drug methods.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.