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The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

Some treatments work better for different types of hair loss, and nutrients like iron and L-lysine are important for preventing hair loss.

Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Rodent models helped understand psoriasis but none perfectly replicated the disease.

People with alopecia areata often experience negative personal, social, and medical impacts, and need psychological support.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Treating generalized granuloma annulare is difficult, with PUVA being the most effective option, but relapses are common.

Alopecia areata is complex, often recurring, and needs personalized treatment, especially with other health issues.

Alopecia areata treatment varies, with no optimal method established yet.

Physical inactivity is a primary cause of many human illnesses.

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.

Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.

Emotional stress can trigger intermittent hair loss in chronic telogen effluvium, which may not improve with treatment if stress continues.

A woman with anorexia developed gout from self-induced vomiting.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

A toddler's chronic finger ulcer was successfully treated after removing a hair causing hair-thread tourniquet syndrome.