48 citations
,
September 2020 in “Frontiers in Immunology” In this study, researchers found that loss of OGG1 in a mouse model of systemic lupus erythematosus increased IFN-driven immune responses and aggravated skin lesions, suggesting a protective role for OGG1 in SLE skin disease.
47 citations
,
March 2017 in “Clinical, cosmetic and investigational dermatology” This review discusses the link between Parkinson's disease and dermatological disorders, highlighting that skin biomarkers may aid in the diagnosis of Parkinson's, but it reports no new clinical results.
9 citations
,
January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
7 citations
,
October 2013 in “British Journal of Dermatology” This article describes how HIV-related skin disorders vary in presentation among pigmented skin types and highlights challenges in their diagnosis due to atypical disease manifestations.
2 citations
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January 2014 in “Medical Principles and Practice” This study found that patients with rosacea had significantly more radiological evidence of chronic rhinosinusitis, and erythematotelangiectatic severity was associated with CRS.
August 2025 in “Libyan Medical Journal” This study found that patients with vitiligo or alopecia areata have higher levels of anxiety and depression compared to healthy individuals, though no significant differences were observed between the two patient groups, highlighting the psychological impact of these dermatological conditions.
October 2024 in “Our Dermatology Online” This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.
29 citations
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November 2013 in “Expert Review of Dermatology” This article reviews potential causes and treatments for sensitive skin and reports no new clinical results; the authors emphasize neurogenic inflammation and cosmetic choices as key factors in managing the condition.
56 citations
,
March 2015 in “Cell death and differentiation” This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.
research Skin
2 citations
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January 2011 in “Elsevier eBooks” This review discusses approaches to diagnosing and managing cutaneous manifestations of lupus erythematosus and reports no new clinical results.
105 citations
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February 2017 in “British Journal of Dermatology” This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.
70 citations
,
July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” This study found that Schistosoma mansoni cercariae stimulate epidermal keratinocytes in mice, initiating pro-inflammatory responses and barrier repair mechanisms akin to those in wound healing.
38 citations
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March 2019 in “International Wound Journal” In this study, a new cell-tissue technology using a patient's own skin to create a full-thickness skin autograft successfully treated a chronic wound larger than 200 cm², achieving complete functional skin coverage within 12 weeks and maintaining results at a 6-month follow-up.
17 citations
,
June 2016 in “Croatian Medical Journal” In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.
17 citations
,
February 2012 in “Cutaneous and Ocular Toxicology” This study found that xerosis and pruritus are prevalent in patients with chronic renal failure undergoing hemodialysis, highlighting the importance of early recognition of skin issues to alleviate discomfort and reduce complications.
9 citations
,
November 2020 in “Journal of Inflammation Research” This perspective highlights the role of inflammation in male and female pattern hair loss and its implications for developing future therapeutic options.
5 citations
,
January 2019 in “Elsevier eBooks” This chapter reviews skin components, wound healing mechanisms, and the potential of biomaterials to enhance skin repair and regeneration, without offering new experimental results.
5 citations
,
August 2015 in “Sultan Qaboos University medical journal” This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.
2 citations
,
February 2021 in “Journal of comparative pathology” In this study, hyperplastic layers of scabietic sheep skin showed expansive keratin labeling, indicating altered keratin expression compared to healthy skin.
1 citations
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March 2021 in “Phytomedicine plus” This study in male rats found that Cernitin™ significantly relieved pain and decreased prostate weight in models of chronic prostatitis and benign prostatic hyperplasia, suggesting an anti-inflammatory effect.
June 2026 in “International Journal of Bioprinting” This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
This chapter provides an overview of terminology for various skin lesions, including primary and secondary types, but does not report new findings or results.
28 citations
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September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
October 2011 in “Dermato-endocrinology” Hormones significantly affect skin health, with vitamin D playing a key role.
105 citations
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January 2010 in “Mediators of Inflammation” This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.
70 citations
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February 2019 in “The journal of immunology/The Journal of immunology” This study found that short-chain fatty acids produced by the skin microbe Propionibacterium acnes may drive inflammatory gene expression in sebocytes, potentially contributing to acne.
47 citations
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September 2023 in “Pharmacological Reports” In this review, researchers explored the roles of vitamins A, B3, C, D, and E in skin immunity, highlighting their potential as therapeutics for skin diseases due to their antioxidant, anti-inflammatory, and antimicrobial properties.
12 citations
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June 2024 in “Archives of Dermatological Research” This scoping review found a high prevalence of skin conditions among older people living at home, but available evidence on burden and effective care strategies is limited.