April 2014 in “The FASEB journal” The extract helps prevent hair loss and promotes hair growth in stressed mice.
417 citations,
March 1991 in “American Journal of Psychiatry” Most adult chronic hair pullers are women who started in their early teens, often have other mental health issues, and may pull hair due to underlying psychiatric conditions.
109 citations,
July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
71 citations,
November 2013 in “Clinics in Dermatology” Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
59 citations,
March 2013 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.
59 citations,
April 2011 in “Retina-the Journal of Retinal and Vitreous Diseases” Finasteride may help treat chronic CSC, improving vision.
57 citations,
December 2021 in “Advanced Functional Materials” Wearable bioelectronics show promise for improving chronic wound care.
54 citations,
October 2019 in “Cochrane library” Some drugs may reduce prostatitis symptoms short-term with few side effects.
50 citations,
May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
41 citations,
November 1993 in “Journal of The American Academy of Dermatology” DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.
40 citations,
April 2013 in “Dermato-endocrinology” People with chronic Alopecia Areata often have lower vitamin D levels.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
30 citations,
August 2016 in “Advances in radiation oncology” Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
29 citations,
July 2004 in “Pharmacology, Biochemistry and Behavior” Finasteride reduces alcohol withdrawal effects, especially in female mice.
25 citations,
September 1977 in “Journal of Toxicology and Environmental Health” The study investigated the chronic toxicity of contraceptive steroids in female beagle dogs, using doses 1, 10, or 25 times higher than those for humans. It found that dogs treated with norethindrone-ethynylestradiol and dimethisterone-ethynylestradiol developed cystic endometrial hyperplasia, pyometra, and alopecia, but did not show significant mammary development or related hyperplastic/neoplastic changes. However, dogs on high doses of megestrol acetate exhibited significant mammary stimulation, hyperplastic and neoplastic changes, and symptoms of diabetes mellitus. These mammary changes, including nodular hyperplasia and tumors, were not observed in similar studies on monkeys or rats, raising questions about their relevance to human tumorigenesis.
23 citations,
January 2007 in “Archives of Andrology” Finasteride may negatively affect male fertility.
21 citations,
June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
19 citations,
September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
18 citations,
June 2002 in “BJUI” Finasteride doesn't change rat testicle weight or sperm production.
16 citations,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
13 citations,
February 2019 in “Türk oftalmoloji dergisi” New treatments for chronic central serous chorioretinopathy show promise in preventing permanent vision loss.
11 citations,
March 2016 in “Journal of the European Academy of Dermatology and Venereology” Almost all patients with chronic kidney disease not yet on dialysis have at least one skin problem.
11 citations,
August 1948 in “Journal of Investigative Dermatology” Calcium pantothenate therapy improved symptoms of discoid lupus erythematosus without side effects.
10 citations,
June 2019 in “Dermatologic therapy” DPCP alone is more effective and safer for treating chronic extensive alopecia areata than combining it with anthralin.
8 citations,
September 2013 in “Journal of Social Service Research” Lupus causes emotional and social challenges, but support from friends helps reduce depression and anxiety.
4 citations,
May 2019 in “Biology open” Testosterone reduces heart damage and inflammation after injury.
3 citations,
November 2020 in “Phyton-international Journal of Experimental Botany” Wedelolactone may help treat chronic diseases by acting as an antioxidant and affecting important proteins.
3 citations,
March 2020 in “International Journal of Dermatology” Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.
2 citations,
January 2021 in “Cureus” A child's chronic use of Senna caused liver damage and a severe decrease in blood cells, but improved after stopping Senna and getting treatment.
1 citations,
July 2014 in “Nepal journal of dermatology, venereology & leprology” Patients with chronic kidney disease on hemodialysis often have skin problems.