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Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

Cyclosporine is effective for skin conditions but has declined in use due to toxicity concerns.

Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.

Rodent models helped understand psoriasis but none perfectly replicated the disease.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Endocannabinoids help control mast cell activity in human skin.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Demodex mites can cause skin issues, especially in people with weak immune systems.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Hidradenitis suppurativa is a skin condition possibly caused by hair follicle issues, with treatments focusing on infection and inflammation.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

Generalized vitiligo in Chinese patients is linked to other autoimmune diseases, especially in familial cases.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

The conclusion is that there's a need for a new conference to establish stricter guidelines for diagnosing Polycystic Ovary Syndrome (PCOS).

Low iron and vitamin D levels are linked to hair loss in women.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

K16 can partially replace K14 but causes hair loss and skin issues.