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This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.

This review discusses the mechanisms and grading challenges of acne vulgaris, highlighting the need for better treatment strategies and reports no new experimental results.

This review assesses the potential of smart dressings, engineered to respond to various stimuli, as advanced treatments for chronic inflammatory skin diseases by examining their activation mechanisms and proposing future developments like integrating AI and closed-loop monitoring for adaptive therapy.

This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.

This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This review found that insulin resistance is a significant independent factor in the development of various inflammatory skin diseases, often linked with obesity and metabolic disorders, and suggests measuring HOMA-IR in affected patients.

Permanent hair loss after a stem cell transplant can be a sign of chronic immune system attack on the scalp.

This study reviewed the use of dupilumab, beyond its approved indications for atopic dermatitis and prurigo nodularis, and found effective treatment reports for various chronic inflammatory skin diseases such as bullous autoimmune diseases, eczema, and alopecia areata, highlighting its broad potential in dermatology.

This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.

This review discusses the potential benefits of nonantibiotic macrolides for treating inflammatory skin disorders and reports no new clinical results.

This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.

In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.

This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

This study observed that individuals with androgenetic alopecia had abnormal correlations in hematologic parameters, suggesting a chronic, slowly progressing immune-related disorder tied to pubertal androgen secretion.

This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.

This review describes evidence suggesting regular apple consumption may improve cardiovascular health and reduce risks for chronic diseases through antioxidant, anti-inflammatory, and other beneficial effects, particularly when consumed as whole fruits rather than processed forms.

This review examines the role of autoinflammation and immune dysregulation in hidradenitis suppurativa, linking it to genetic factors and autoinflammatory syndromes, but highlights the need for further research to fully understand its pathogenic mechanisms.

This review explores the inflammatory pathogenesis and clinical presentation of hidradenitis suppurativa, highlighting the complexity of treatment and the impact on patients' quality of life, while also examining emerging therapeutic options.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This paper discusses insulin resistance's effects on skin physiology, emphasizes its role in keratinocyte balance, and reports no new experimental findings.

This article reviews historical cases and descriptions of perifolliculitis capitis abscedens et suffodiens, highlighting its characteristics and treatment, but reports no new clinical findings.

This mini review discusses insights into the pathogenesis of hidradenitis suppurativa, highlighting genetic mutations, autoinflammation, and the effectiveness of biologics, and introduces the concept of autoinflammatory keratinization disease, without reporting new clinical results.

This study concluded that myositis in the reported case was caused by T-cell large granular lymphocytic leukemia, not dermatomyositis.

This study evaluated interleukin-26's antimicrobial activity in Hidradenitis Suppurativa and explored its potential role in chronic skin inflammation.

This review discusses the use of single-cell RNA sequencing and spatial transcriptomics to enhance understanding of the pathogenesis and targeted therapies for chronic inflammatory skin conditions, highlighting technology advancements and the need for cost reduction and standardization.

This review highlights that nano-antioxidants show promise as a treatment strategy for immune-mediated inflammatory diseases, like autoimmune and chronic inflammatory conditions, due to their improved stability and targeted delivery, but notes that further research is necessary to optimize their use and assess long-term safety.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

This study found that administering gingerol improved survival and reduced organ damage in mouse models of chronic graft-versus-host disease by modulating T cell differentiation and inflammatory cytokines, suggesting a novel therapeutic approach for steroid-refractory cases.

This study found that activation of cannabinoid 1 receptors in human scalp hair follicles may limit excessive mast cell activation and maturation, suggesting a potential therapeutic strategy for managing MC-dependent skin diseases.

This study reports two cases of alopecia associated with anti-TNF therapy, highlighting a new entity combining features of alopecia areata and psoriatic alopecia.