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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

HIV can cause unusual and severe skin problems that are hard to treat.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Stem cell therapy may help treat tough hair loss cases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Hedychium spicatum has medicinal properties but needs more research for scientific validation and use.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Honokiol helps protect skin from damage and aging caused by cigarette smoke.