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A young woman with severe symptoms of CPAN improved with intensive treatment but needed a leg amputation.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.

Different parts of the body have unique immune characteristics in their skin.

Micropigmentation is a cosmetic tattooing technique for hiding skin issues and creating permanent makeup, but it can have side effects.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Teriflunomide is effective and generally safe for treating relapsing multiple sclerosis, reducing relapse rates and disability progression.

Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.

Pregnancy can cause skin changes and conditions that need correct diagnosis and treatment for the health of the mother and baby.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Early diagnosis and treatment of nail and skin conditions can improve health and appearance.

The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.

Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.