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Rapamycin increased survival in mice with severe chronic graft-versus-host disease by expanding regulatory T cells.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

Stem-cell therapy shows promise for skin conditions but needs more research.

Mesenchymal stem cells are effective and safe for treating various diseases in children.

HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Voriconazole can cause serious side effects, especially in long-term use.

People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

Tyrosine kinase inhibitors show promise in treating some skin diseases but their definitive role in dermatology is still unclear.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Special fiber materials boost the healing properties of certain stem cells.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

High-frequency ultrasonography is a useful but underused tool in dermatology for assessing skin cancers, monitoring diseases, and evaluating treatments.