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The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Chromosomal differences affect how muscle cells respond to testosterone.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.

Betamethasone dipropionate reduced skin thickness, fish oil increased it, and combined treatment had no significant effect.

A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

New treatments targeting specific genes show promise for treating keratin disorders.

JAK inhibitors show promise in effectively treating hair loss from alopecia areata.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.

Two mouse mutations cause similar hair loss despite different skin changes.

The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.

Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

HOXC13 is essential for hair and nail development by regulating Foxn1.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

A new therapy for a skin blistering condition has not been developed yet.

Reversing female hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.