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Hormones and genes affect hair growth and male baldness.

The RORα gene is active in different parts of cashmere goat hair follicles and may be influenced by melatonin, especially in December when hair growth changes.

Two mouse mutations cause similar hair loss despite different skin changes.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Different scalp and hair disorders are more common in certain ethnic groups, with the most common being androgenetic alopecia, which is treated with medications like minoxidil and finasteride.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.