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Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Discontinuing topical minoxidil can resolve headaches and dizziness.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Methotrexate side effects vary by race and sex.

Nurses are exposed to chemotherapy drugs, risking health issues like hair loss, so protective gear and monitoring are needed.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.

Non-immune factors play a significant role in alopecia areata.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

A Turkish family with sparse hair and eyebrow loss has a mutation in the U2HR gene linked to Marie Unna hereditary hypotrichosis.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.