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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

PGD2 stops hair growth and is higher in bald men with AGA.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lactate production is important for activating hair growth stem cells.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Fungi-produced compounds can change plant root growth.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Some medicinal plants can help heal wounds and may lead to new treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Finasteride safely lowers DHT levels without affecting testosterone.

Too much androgen can cause hair loss; finasteride may help.

Androgens, like testosterone, are crucial for early testicular descent in rats.