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The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Cell aging can be both good and bad for tissue repair.

Skin organoids are a promising new model for studying human skin development and testing treatments.

CIP/KIP proteins help stop cell division and support hair growth.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Mutations in certain receptors can cause diseases and offer new treatment options.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Telogen is an active phase with important biological processes, not a resting phase.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.