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Apoptosis is essential for human skin development and forming a functional epidermis.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Different types of skin cells play specific roles in development, healing, and cancer.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Scientists created stem cells that can grow hair and skin.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.