research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
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research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes
Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
research Notch1 Signaling Regulates Wound Healing by Changing the Characteristics of Epidermal Stem Cells
Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
research A Polymorphism in the Matrix Metalloproteinase-1 Gene Promoter Is Associated with the Presence of Polycystic Ovary Syndrome in Caucasian Women
A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.
research Proliferation, DNA Repair, and Apoptosis in Androgenetic Alopecia
Bald areas have lower cell growth, more DNA damage, and increased cell death.
research Blockades in the Pathway of Specialty Care in Systemic Lupus Erythematosus: A Report Based on Indian Rheumatology Association Database
Educating primary care doctors and improving referrals to rheumatologists can reduce delays in treating lupus patients.
research Evaluation of the Relationship of Digital Phototrichogram Findings with Blood TSH, Ferritin, and Vitamin B12 Levels in Patients with Diffuse Hair Loss
Low ferritin levels are linked to increased hair loss; no link found between vitamin B12, TSH levels, and hair loss.
research Analyses of Regenerative Wave Patterns in Adult Hair Follicle Populations Reveal Macro-Environmental Regulation of Stem Cell Activity
Hair follicle stem cells are controlled by their surrounding environment.
research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin
Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.
research Sphingolipids of the Murine Hair
Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.
research Flavonoids with Two Hydroxyl Groups in the B-Ring Promote Pigmented Hair Regeneration
Certain flavonoids help grow back colored hair after skin injury.
research Sodium Valproate: Doctor Jekyll and Mister Hyde
Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
Loss of Msx2 function causes eye development issues similar to Peters anomaly.
research Valence-Engineered Catalysis-Selectivity Regulation of Molybdenum Oxide Nanozyme for Acute Kidney Injury Therapy and Post-Cure Assessment
A specially designed molybdenum oxide nanozyme can treat and monitor acute kidney injury effectively.
research Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
research A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle
Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
research C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Ectodermal Organ Stem Cells: Morphogenesis, Population Regenerative Behavior, and Evolutionary Development
Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.
research Self-Organizing Hair Peg-Like Structures From Dissociated Skin Progenitor Cells: New Insights for Human Hair Follicle Organoid Engineering and Turing Patterning in an Asymmetric Morphogenetic Field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Functional Salivary Gland Regeneration by Transplantation of a Bioengineered Organ Germ
Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
research Studies on Microscopic Identification of Animal Drugs’ Remnant Hair: Identification of Several Species of Cauda Cervi
Microscopic hair features can identify different Cauda Cervi species.
research Preparation and Optimization of Garlic Oil/Apple Cider Vinegar Nanoemulsion Loaded with Minoxidil to Treat Alopecia
The nanoemulsion with garlic oil, apple cider vinegar, and minoxidil could effectively treat alopecia areata.
research Promotion of Mouse Ameloblast Proliferation by Lgr5 Mediated Integrin Signaling
CD61 is important for mouse tooth cell growth and works through Lgr5.
research Comparison Between Melatonin, Melatonin and Photobiomodulation, and Photobiomodulation in the Treatment of Alopecia X in German Spitz Dogs: Clinical, Randomized, Double-Blind, Parallel, Non-Inferiority Protocol
Melatonin and photobiomodulation are effective for treating Alopecia X in German Spitz dogs.
research Suppression of Wnt/β-Catenin Signaling by EGF Receptor Is Required for Hair Follicle Development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Skin stem cells in hair follicles are important for touch sensation.
research Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration
Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
research Generation of a Gene Expression Signature for Sebaceous Glands by Transcriptome Comparison of Psoriasis and Sebaceous Hyperplasia
Sebaceous gland atrophy and abnormal function may contribute to hair loss in psoriasis.
research MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.