research Is Xanthine Oxidase Activity in Polycystic Ovary Syndrome Associated with Inflammatory and Cardiovascular Risk Factors?
Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.
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research Congenital Adrenal Hyperplasia: A Review of 21-Hydroxylase Deficiency and Diagnostic Challenges
The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.
research A Topical Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor Antagonist Stimulates Hair Growth in Mice
A cream with a specific hormone blocker increases hair growth in mice.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Liposomes with an Ethanol Fraction as an Application for Drug Delivery
Ethosomes improve drug delivery through the skin but may have side effects like irritation.
research Androgenetic Alopecia and Risk of Coronary Artery Disease
Balding people may have higher heart disease risk.
research Applications of Steroid Drugs Entrapped in Cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Scalp Hair Regrowth in Hormone-Treated Transgender Woman
Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
research Sex-Specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids
Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
research Ginsenoside F2 Reduces Hair Loss by Controlling Apoptosis Through the Sterol Regulatory Element-Binding Protein Cleavage Activating Protein and Transforming Growth Factor-β Pathways in a Dihydrotestosterone-Induced Mouse Model
Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.
research Exogenous and Endogenous Lipids of Human Hair
Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
research Association of Metabolic Syndrome With Female Pattern Hair Loss in Women: A Case-Control Study
Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.
research Metabolic Syndrome in Greek Women with Polycystic Ovary Syndrome: Prevalence, Characteristics, and Associations with Body Mass Index. A Prospective Controlled Study
Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
research Transfollicular Enhancement of Gel Containing Cationic Niosomes Loaded with Unsaturated Fatty Acids in Rice Bran Semi-Purified Fraction
The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
research Clinical Case Seminar: Postmenopausal Androgen Excess - Challenges in Diagnostic Work-Up and Management of Ovarian Thecosis
The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
research Association Between Androgenetic Alopecia and Coronary Artery Disease in Young Male Patients
Hair loss linked to heart disease in young men.
research The Effect of Finasteride and Dutasteride on the Synthesis of Neurosteroids by Glioblastoma Cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Assessment, Diagnosis, and Treatment of a Patient with Hirsutism
A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
research Physiopathological Role of the Enzymatic Complex 5α-Reductase and 3α/β-Hydroxysteroid Oxidoreductase in the Generation of Progesterone and Testosterone Neuroactive Metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Characterization of Metabolic Changes in the Phenotypes of Women with Polycystic Ovary Syndrome in a Large Mediterranean Population from Sicily
Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.
research Skin and Glucocorticoids: Effects of Local Skin Glucocorticoid Impairment on Skin Homeostasis
Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
research Distribution of Glycolipid and Unsaturated Fatty Acids in Human Hair
Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats
research The Degree of Premature Hair Graying as an Independent Risk Marker for Coronary Artery Disease: A Predictor of Biological Age Rather Than Chronological Age
Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.
research Patients With Vitiligo Present Fewer Cardiovascular Risk Factors: Results From a Case-Control Study
People with vitiligo may have a lower risk of heart disease.
research Hirsutism, Postpartum Telogen Effluvium, and Male Pattern Alopecia
Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.