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Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

PEVs improve minoxidil skin penetration, increasing hair growth.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Finasteride effectively treats baldness but may cause sexual side effects.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Testosterone's muscle-building effects do not require its conversion to DHT.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.