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The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.

Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.

Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The new formulation improved the skin absorption of the drug Thiocolchicoside.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The Cross-section Trichometer is a new tool that can measure hair quantity and detect hair loss and growth.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.