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Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

More research is needed to understand how testosterone is maintained in adult males.

Olive and olive oil help prevent and manage heart diseases.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

The document explains how male reproductive hormones work and affect the body.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

The document concludes that more research is needed to fully understand the causes of PCOS.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.