10 citations
,
January 2022 in “Scholars international journal of anatomy and physiology” This review discusses Aloe Vera's traditional uses and active components but reports no new clinical results, emphasizing its potential benefits from wound healing to hair growth.
10 citations
,
May 2018 in “Neuropharmacology” This study suggests that inhibitors of steroidogenic enzymes may have therapeutic potential for certain behavioral disorders linked to dopaminergic hyperfunction, despite concerns about their endocrine impacts.
10 citations
,
November 2016 in “International Journal of Cosmetic Science” This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.
9 citations
,
March 2020 in “Gene” In this study, certain genetic variations in the ESR1 and ESR2 genes were strongly associated with polycystic ovary syndrome and related metabolic issues in Tunisian women.
9 citations
,
May 2019 in “Experimental Cell Research” This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
9 citations
,
November 2018 in “Journal of cosmetic dermatology” This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.
9 citations
,
May 2012 in “PLOS ONE” This study found that integrin-linked kinase is crucial for various epidermal functions, including differentiation and barrier formation, and also plays a previously unreported role in melanocyte development and function.
8 citations
,
September 2024 in “BMC Genomics” In this study, researchers found that the novel gene circCFAP20DC enhances the proliferation of goat follicular granulosa cells by activating the RB pathway, facilitating their progression from the G1 to S phase during follicular development.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” This review discusses the roles of adiponectin and bradykinin in skin homeostasis and pathologies, highlighting the need for further research into their therapeutic potential but reports no new clinical results.
8 citations
,
December 2021 in “International Journal of Family Studies, Food Science and Nutrition Health” This review discusses the potential health benefits and applications of extra virgin olive oil as a nutritional therapeutic immune-enhancer, but reports no new clinical findings.
8 citations
,
June 2019 in “Scientific Reports” This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.
8 citations
,
May 2017 in “IUBMB life” This review discusses the role of astrotactins in development and their genetic mutations' links to a variety of human diseases, but reports no new clinical results.
8 citations
,
February 2014 in “General and Comparative Endocrinology” In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.
7 citations
,
September 2024 in “Scientific Reports” This study suggests that sebum samples can be effectively stored and transported with less stringent requirements than liquid samples, making them suitable for remote or at-home collection before clinical analysis.
7 citations
,
September 2024 in “Applied Microbiology and Biotechnology” In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.
7 citations
,
June 2024 in “Communications Medicine” In this study, researchers analyzed spaceflight data from various sources and found that skin issues during spaceflight are linked to DNA damage, mitochondrial dysregulation, and gene alterations, while also highlighting the skin's adaptability post-flight.
7 citations
,
January 2022 in “Animal Reproduction” This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.
7 citations
,
July 2021 in “Molecules/Molecules online/Molecules annual” This study demonstrated that an LC/MS-MS method could effectively detect and quantify the vitamin B3 vitamer nicotinamide in human hair, suggesting its potential use for long-term deficiency examination.
7 citations
,
August 2017 in “PloS one” This study found that NIH hairless mice exhibit abnormalities in hair growth and immune-related pathways, with Pik3r1 and Pik3r3 identified as key genes for further investigation.
7 citations
,
January 2015 in “Genetics and molecular research” This study suggests melatonin may promote cashmere growth in Inner Mongolian cashmere goats through the nuclear receptor RORα, with a noted mRNA expression difference in December compared to other months.
7 citations
,
January 2012 This study used artificial neural networks to predict hair loss by analyzing factors like gender and zinc deficiency, suggesting neural networks may effectively model hair loss prediction.
6 citations
,
March 2021 in “Cytotechnology” This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.
6 citations
,
January 2012 in “Breast cancer” This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.
6 citations
,
January 2009 in “Elsevier eBooks” This chapter discusses the structure and function of the skin, detailing its protective roles and the layers that comprise it, but reports no new research findings.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
5 citations
,
March 2024 in “Acta Scientiarum Polonorum Technologia Alimentaria” This study synthesized existing research on 11 tropical seed varieties, underscoring their potential in food, pharmaceutical, and agricultural industries due to their phytochemicals and nutrients, such as phenolics and vitamins, which could reduce waste and support sustainable practices.
5 citations
,
May 2023 in “Frontiers in immunology” This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.
5 citations
,
May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
5 citations
,
May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.