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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

Gastric exclusion surgery caused major weight loss and health improvements but led to some anemia and vitamin deficiencies.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Balding people may have higher heart disease risk.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Low-level laser therapy improves hair growth and dermal papilla cell function.

Alcohol in teen years leads to more adult drinking, finasteride doesn't help.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.