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Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

New genes and pathways are important for testosterone production and male sexual development.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Skin health and diseases are closely linked to metabolic processes.

Decanoic acid may help treat PCOS by reducing androgen levels and improving glucose sensitivity.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Neurosteroids show promise for treating epilepsy and more research is needed.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.