research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
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research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Cosmeceuticals in Dermatology
Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research Use of Oral Contraceptives in the Management of Acne
Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.
research Hereditary, Congenital, and Acquired Alopecias in Dogs and Cats
The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.
research Pathogenesis and Causes of Hirsutism
Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
research The Cat With Alopecia
Cats lose fur due to various reasons, including allergies, infections, genetics, hormones, diet, cancer, stress, and some conditions are treatable while others are not.
research Polycystic Ovarian Disease: Current Insights and Therapeutic Strategies
Combining lifestyle changes and medication is most effective for managing PCOS symptoms.
research Activity of Isoflavone in Managing Polycystic Ovary Syndrome Symptoms: A Review
Isoflavone may help manage PCOS symptoms, but its effectiveness is uncertain.
research Case Report: A Novel Splice-Site Mutation of MTX2 Gene Caused Mandibuloacral Dysplasia Progeroid Syndrome: The First Report from China and Literature Review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
research Robotic Hair Transplantation – Artificial Intelligence Plus Human Touch
Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.
research Dianabol Unveiled: A Systematic Review of Methandrostenolone
Dianabol boosts muscle growth but has serious health risks and legal issues.
research Advances in the Treatment of Autosomal Recessive Congenital Ichthyosis: A Look Towards the Repositioning of Drugs
Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.
research Predisposing and Overall Effects of Reproductive Hormones on Breast Cancer: A Review
Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
research Vitamin B-Complex and Its Relationship With the Health of Vegetarian People
Vegetarians should take B vitamin supplements to avoid health issues.
research Polycystic Ovarian Syndrome Revisited
PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.
research Associations Between Serum Dihydrotestosterone Levels, Lipid Parameters, and Anthropometric Measurements in Male Patients with Type 2 Diabetes Mellitus
Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.
research Vitamin D in Dermatology and Cosmetology
Vitamin D is crucial for skin health and managing skin diseases.
research Clinical and Molecular Genetic Studies in Hereditary Hair Loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
research Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Health Is Wealth and Wealth Is Pugos Nutrition
Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Endocrinology Overview: Male Reproductive Endocrinology and HPT Axis
The document explains how male reproductive hormones work and affect the body.
research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability
Early NAS level changes affect alcohol consumption vulnerability.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.