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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.