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Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

People with lichen planus are more likely to have abnormal blood fats than healthy people.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Liposomes better deliver minoxidil for hair loss treatment than niosomes.

EDA2R gene linked to hair loss.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.