research MendelVar: Gene Prioritization at GWAS Loci Using Phenotypic Enrichment of Mendelian Disease Genes
MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.
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research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Androgenic Alopecia, Premature Graying, and Hair Thinning as Independent Predictors of Coronary Artery Disease in Young Asian Males
Early balding, premature graying, and hair thinning can predict heart disease in young Asian males.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Sphingolipids of the Murine Hair
Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.
research Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment
Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.
research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
research Type A Insulin Resistance Syndrome Due to a Novel Heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR Gene Mutation in an Adolescent Girl and Her Mother
A new gene mutation causes insulin resistance in a girl and her mother.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Oral Tofacitinib in Moderate and Severe Alopecia Areata: Case Series of 14 Patients
Tofacitinib helped regrow hair in most patients with severe hair loss.
research Progress in Diagnosis and Treatment of Polycystic Ovary Syndrome with Traditional Chinese and Western Medicine
Combining Traditional Chinese Medicine and Western medicine can improve symptoms, hormone levels, and pregnancy outcomes in Polycystic Ovary Syndrome patients, but more research is needed.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
research Acne-Associated Syndromes
Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
research Hallmark Evidence of Lipopolysaccharide Tolerance in Obese Women with Polycystic Ovary Syndrome: LPS-Induced NFkB Suppression in Mononuclear Cells Linked to Hyperandrogenism
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
research Tissue and Circulating MicroRNA Co-Expression Analysis Reveals Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia
Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
research Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases
The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
research Establishment and Characterization of Human Sebocytic Progenitor Cells That Can Differentiate Into Functional Sebocytes
Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Disorders of Keratinization
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
research Topical Sunscreens and Vitamin D
Hair loss treatments show limited improvement, sunscreen thickness affects vitamin D production, and the effectiveness of IVIg for toxic epidermal necrolysis is uncertain.
research Skin Signs Due to Starvation
Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.