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PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Boosting mitochondrial energy production with supplements like acetyl-L-carnitine may improve aging-related cellular function and health conditions.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Skin problems are very common in people with end-stage kidney disease.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.