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Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Herbal nano-formulations show potential for effective skin delivery but need more research.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.

Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.