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Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Patients with acne and insulin resistance have different blood metabolites compared to those with only acne, which could help in diagnosis and treatment.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

More research is needed to understand how testosterone is maintained in adult males.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Acitretin treats severe skin conditions but requires careful monitoring due to serious side effects.

The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.

Certain hairstyles, diabetes, scalp infections, and vitamin D deficiency may increase the risk of hair loss in Black women; more research is needed for better treatment.

Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Some natural extracts and one hair tonic can promote hair growth in mice.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.

JAK inhibitors may soon be a safe and effective treatment for alopecia areata.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

A man had rare skin tumors with bone formation and cholesterol deposits.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

Computational methods can speed up and improve the development and safety of herbal drugs.

Off-label drug use can be risky but sometimes beneficial when standard treatments fail.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.