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The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Liposomes better deliver minoxidil for hair loss treatment than niosomes.

A new gene, JMJD1C, may affect testosterone levels in men.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Nonionic liposomes are the best for delivering genes to skin cells.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Testosterone may slow down wound healing and increase inflammation.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Obese women with PCOS are more likely to have fatty liver disease.

Early balding men may have insulin resistance, but lifestyle changes can help.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.