This study in women aged 28-38 after their first cesarean delivery found higher levels of inflammatory markers and metabolic disturbances, including elevated BMI and blood sugar, which may contribute to increased postpartum hair loss compared to healthy controls.
January 2020 in “Indian Journal of Pharmaceutical Sciences” In this study, combining Kuntai capsules with nilestriol tablets for three months was found to reduce symptoms of perimenopausal syndrome and improve reproductive hormone levels more effectively than nilestriol alone; however, the benefits did not persist significantly beyond three months.
April 2019 in “Journal of Investigative Dermatology” This study observed that simvastatin promoted hair regrowth in a mouse model of alopecia areata by reducing inflammatory markers and T cell proliferation, partly through disruption of isoprenoid metabolite production.
January 2008 in “Annals of Biomedical Sciences” This study found that water extracts of Spondias mombin bark led to significant recovery in rats with induced cancer, while alcohol extracts did not produce significant effects.
22 citations
,
June 2012 in “PLOS ONE” In this study, researchers found that impaired cholesterol biosynthesis in hair follicles may trigger an inflammatory immune response linked to primary cicatricial alopecia, providing new insights into the disorder's pathogenesis.
3 citations
,
April 2019 in “Human & Experimental Toxicology” This study found that finasteride caused adverse effects on liver, kidney, and heart tissues in female mice, raising concerns about its potential use in females for treating androgenetic alopecia.
25 citations
,
July 2019 in “Experimental Dermatology” This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.
42 citations
,
January 2011 in “Journal of Biomedical Optics” This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
24 citations
,
June 2011 in “International Journal of Dermatology” This review summarizes physiologic skin changes during pregnancy and specific pregnancy-related dermatoses but reports no new clinical results.
12 citations
,
May 2015 in “Molecular Medicine Reports” This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.
10 citations
,
August 2014 in “Skin research and technology” This study found that variations in sleep patterns, free testosterone, and 5-alpha-reductase type 1 activity are associated with changes in sebum excretion in women, which may contribute to variability in acne studies.
6 citations
,
March 2016 in “British Journal of Dermatology” This study reports that low levels of HDL cholesterol and IGF-1 were associated with a higher risk of hair loss in middle-aged women, but causal relationships remain uncertain.
September 1998 in “Journal of the European Academy of Dermatology and Venereology” This article reviews the role of androgen in male pattern hair loss and its impact on hair follicle miniaturization, but it does not present new research findings.
86 citations
,
February 2009 in “Journal of Neuroscience” This study found that during late pregnancy in rats, there is an increase in extrasynaptic GABA A receptor number in granule cells of the dentate gyrus, linked to hormonal fluctuations.
62 citations
,
April 2013 in “Steroids” This review discusses the age-related diagnostic challenges and comorbidities of polycystic ovarian syndrome and provides no new clinical findings; the authors emphasize the role of obesity in insulin resistance among affected women.
18 citations
,
July 2019 in “Clinical Endocrinology” The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.
7 citations
,
October 2020 in “Journal of Clinical Medicine” In this study, researchers found that overweight and obese women with polycystic ovary syndrome showed adverse changes in glucose metabolism over time, highlighting the importance of early intervention to prevent cardiometabolic diseases.
September 2021 in “Research Square (Research Square)” This study found that measuring specific steroid hormone levels can aid in diagnosing P450 oxidoreductase deficiency, a subtype of congenital adrenal hyperplasia, by distinguishing affected patients from healthy individuals.
71 citations
,
June 2006 in “Human Reproduction” This study found that in young Taiwanese women with PCOS, low sex hormone-binding globulin levels were associated with low HDL cholesterol levels, independent of insulin resistance and obesity.
6 citations
,
January 2014 in “The Journal of Advances in Parasitology” This study observed that dogs with sarcoptic mange exhibited symptoms like intense itching and restlessness, along with specific haematological and biochemical abnormalities compared to healthy dogs.
5 citations
,
July 2016 in “Journal of Clinical Hypertension” This study found that hypertensive patients with severe androgenic alopecia exhibited impaired coronary microcirculation, suggesting they may face increased cardiovascular risk.
January 1953 in “Nihon Chikusan Gakkaiho” This study found that soaking raw skin in a saturated lime solution led to widespread cellular dissolution and tissue changes that facilitate dehairing after 4 to 7 days at -18°C.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
48 citations
,
February 2008 in “Nutrition in Clinical Practice” This article reviews dietary recommendations for managing polycystic ovary syndrome and provides evidence that diet changes can improve the androgen profile in affected women, but it reports no new clinical results.
2 citations
,
March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
1 citations
,
May 2018 in “Clinical chemistry” This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.
January 2024 in “Wiadomości Lekarskie” This study found that kinematic alignment in total knee arthroplasty leads to a higher proportion of patients requiring smaller femoral components compared to traditional mechanical alignment, with statistical significance observed in femoral sizing differences between the two groups.
16 citations
,
February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.