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The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

A blood pressure drug, diltiazem, may also help treat influenza.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Sex hormones, especially androgens, play a key role in causing acne.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Testosterone may slow down wound healing and increase inflammation.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The circadian clock in skin cells controls their growth and rest cycles.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.