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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Some medicinal plants can help heal wounds and may lead to new treatments.

Myrtle has various health benefits and potential for medicine development.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

Improving skin barrier and using antifungal treatments can help manage dandruff.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.