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This study found that finasteride effectively inhibits the enzymatic activity of human steroid 5 alpha reductase type II in newly established CHO cell lines.

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.

This study found that expressing certain PIN proteins in Arabidopsis root hairs inhibited growth by decreasing auxin levels, while PIN5 slightly stimulated growth, demonstrating differential effects on auxin transport.

This study reports that LL-37 treatment enhances cell proliferation, migration, and secretion of regenerative factors in adipose-derived stem cells, potentially promoting hair growth in vivo.

In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.

This abstract provides information about data availability and author affiliations but does not contain results or conclusions from the study itself.

Among in vitro and in vivo models, this study found that Miscanthus sinensis var. purpurascens flower extract may promote hair growth, potentially by modulating growth factor expressions and facilitating earlier hair follicle transitions in treated mice.

This study found that fibroblast loss in the upper dermis from UVR exposure is linked to a deregulated inflammatory response, with T cells playing a protective role in fibroblast survival.

This study found that the loss of papillary fibroblasts in the skin due to UV radiation is mainly caused by an uncontrolled inflammatory response, with T cells helping fibroblast survival.

This case study reported that a 51-year-old woman with hirsutism and voice thickening had a Leydig cell tumor detected by PET-CT, which normalized hormone levels and resolved symptoms after surgical removal.

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.

This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study found that acute stress in rats inhibits hair growth, likely through increased cortisol levels and activation of the substance P-mast cell pathway.

In this study, researchers found that the cell surface protein Lrig1 plays a crucial role in regulating the suppressive function of regulatory T cells, suggesting it as a potential target for treating autoimmune diseases, as evidenced by experiments in mouse models.

This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.

This study reports that mesenchymal stem cell-conditioned medium promoted dermal cell migration and proliferation, enhancing wound healing but not direct hair growth, in vitro and in adult mouse models.

This study found that a specific fragment of AIMP1, secreted by hair follicle stem cells, activated dermal papilla cells, leading to enhanced hair regrowth and maintenance in mice.

This study suggests that dermal fibroblast-conditioned medium containing multi-peptide factors may stimulate hair growth by enhancing growth factor expression and β-catenin regulation in hair follicle cells.

This study found that treating patients with androgenetic alopecia using exosomes from adipose tissue stem cells over 24 weeks significantly increased hair density and patient satisfaction without severe adverse effects, suggesting a promising alternative treatment for hair loss.

Veratric Acid may help promote hair growth and reduce hair loss.

This study found that neonatal Regulatory T cells are crucial for maintaining PPARγ signaling in hair follicles, which supports melanocyte stem cell function and skin pigmentation during early postnatal development.

This study found that water extract of Puerariae Radix may promote hair growth by increasing the mRNA expression levels of hair growth-related genes in human dermal papilla cells, unlike the juice extract.

This study found that Cynanchi Wilfordii Radix has strong antioxidant activity and may reduce key factors involved in male hair loss in dermal papilla cells.

This study found that targeting mTORC1 with rapamycin effectively inhibited skin tumor promotion in a mouse model, highlighting a potential target for cancer chemoprevention.

This study reveals that hair follicles in mice and humans recruit epidermal Langerhans cells during skin inflammation via specific chemokine signaling pathways.

This study found that minoxidil stimulates hair follicle growth by promoting dermal papilla cell survival and activating ERK and Akt pathways, which leads to increased proliferation and reduced cell death.

This study identified several DPC-specific proteins, including ITGB1, IGFBP3, and THBS1, as potential biomarkers for hair growth modulation through proteomic and network analysis.