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Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The document concludes that drug repurposing, which is reusing known medicines for new illnesses, can provide faster, cheaper treatment options for various serious diseases, including cancer, COVID-19, and rare diseases.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

The exam tested knowledge on various skin-related topics for CME credit.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Lupus can cause different skin problems, and treatments like quitting smoking and using certain creams or medicines can help.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.

Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.

The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Some common medications can harm male fertility, but many effects can be reversed.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Lupus can cause hair loss and nail changes, with treatments available for both.

Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Some skin medications are safe for pregnant women, but others pose risks or should not be used.

Lupus can be a rare cause of high calcium levels in the blood.

Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.