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Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

Activin A increases inner ear hair cell development, while follistatin decreases it.

Patients in Australia underwent costly, unproven stem cell treatments due to weak regulations and aggressive marketing.

The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Raspberry ketone may help grow hair and improve skin elasticity.

GLI2 increases follistatin production in human skin cells.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Eating isoflavone can help mice grow hair by increasing a growth factor.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.