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Some children with localized scleroderma are rarely resistant to methotrexate, and no common profile for resistance was found.

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Hair cortisol could be a marker for chronic stress in pregnancy, but depression affects cortisol levels differently.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

The document concludes that parathyroid diseases have a range of clinical features and outcomes, with some conditions being treatable and others having a high risk of mortality.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

Peginterferon alfa-2b and ribavirin therapy for hepatitis C can cause serious side effects, some different from those reported in clinical trials.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Hair loss was the first sign of a brain-related complication in a woman with lupus, and early treatment helped her hair grow back.

Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

Myotonic dystrophy should be considered in patients with hair thinning, and genetic counseling is important.

The ShorT method can detect and help reduce bias in medical AI by identifying shortcut learning.

Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.

Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.

Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.

Physical activity, height, and smoking affect prostate cancer risk.