December 2024 in “Veterinary Dermatology” This case report identified cutaneous epitheliotropic T-cell lymphoma in a 3-year-old male sugar glider after skin biopsies, highlighting the need for thorough diagnostic evaluations in exotic pets.
November 2024 in “Elsevier eBooks”
September 2024 in “Journal of the European Academy of Dermatology and Venereology” This study found that baricitinib significantly reduced hair loss in patients with severe alopecia areata, decreasing the mean SALT score from 96.6 to 48 over 24 weeks, with no patients dropping out and only mild adverse events in 12.7% of participants.
September 2024 in “Journal of the American Academy of Dermatology” In this study, patients with severe alopecia areata treated with baricitinib over 152 weeks experienced sustained patient-reported improvements in scalp, eyebrow, and eyelash hair regrowth, with higher responders observed in the 4mg dose group compared to the 2mg group.
September 2024 in “Journal of the American Academy of Dermatology” This study found that baricitinib, when administered consistently over three years, maintained its efficacy in patients with severe alopecia areata who responded by Week 52 with notable hair regrowth, indicated by a SALT score of ≤20.
September 2024 in “Journal of the American Academy of Dermatology” Eyebrow and eyelash regrowth usually matches scalp hair response in alopecia areata patients treated with baricitinib.
June 2024 in “JEADV Clinical Practice” This study found that among placebo-treated patients in the BRAVE-AA trials, the likelihood of spontaneous hair regrowth in untreated severe alopecia areata was low, with only a small percentage achieving significant scalp, eyebrow, or eyelash hair improvement over 36 weeks.
This study found that spaceflight may induce skin health risks in astronauts by causing DNA damage and mitochondrial dysregulation, while also identifying gene expression changes that help re-adaptation after returning to Earth.
February 2024 in “BMJ Open” This study at Luigi Sacco University Hospital identified three key macro symptoms of long COVID—neurological, sensorial, and physical—and found that their development is associated with comorbidities, medications during acute COVID-19, and demographic factors like age and gender.
January 2024 in “Medical mycology journal” This study reported three cases of tinea corporis caused by Microsporum canis in a household, linked to a domestic cat, where genetic analysis suggested a familial transmission route.
December 2023 in “Journal of dermatology” This study found that adult and adolescent patients with alopecia areata in the US and Europe are willing to accept significant risks of serious side effects, such as infection and cancer, to achieve effective hair regrowth with Janus kinase inhibitors.
In this study, a strong positive correlation was found between clinician-reported and patient-reported measures for assessing eyebrow and eyelash hair loss in patients with severe alopecia areata, indicating high agreement during treatment with baricitinib over 52 weeks.
This study found that more than half of patients with severe alopecia areata who reduced their baricitinib dose from 4mg to 2mg maintained a clinical response for up to 2 years.
November 2023 in “L'Endocrinologo” This review examines the impact of polycystic ovary syndrome (PCOS) on women's sexual health, highlighting inconsistencies in existing research; it reports no new results.
September 2023 in “Journal of The American Academy of Dermatology” At Week-104 of the BRAVE-AA2 trial, this study found that 90.2% of severe alopecia areata patients who continued on baricitinib 4mg maintained hair regrowth, whereas 45.2% of those who reduced their dosage to 2mg experienced a loss of treatment benefit.
June 2023 in “Dermatology reports” In this report, the authors describe the case of an 83-year-old woman initially diagnosed with atrophic actinic keratosis, but further examination and skin biopsies at their clinic suggested the presence of an inflammatory disease, highlighting the challenges in diagnosing pemphigus.
June 2023 in “British Journal of Dermatology” In this study, baricitinib showed promising results in improving scalp, eyebrow, and eyelash hair loss in adults with severe and very severe alopecia areata over 52 weeks.
January 2023 in “Open veterinary journal” This report describes the first suspected case of dermatologic adverse effects from subcutaneous furosemide in cats, noting ulcerative skin lesions that resolved after switching the formulation.
September 2022 in “Skin appendage disorders” This article explores potential risk factors for central centrifugal cicatricial alopecia and suggests that seborrheic dermatitis may play a role in its development, but it reports no new scientific findings.
July 2022 in “L Endocrinologo” This case report describes a 77-year-old woman with female pattern hair loss and elevated testosterone levels, who showed no improvement with minoxidil and lacked adrenal tumors on imaging.
March 2020 in “Dermatologic Therapy”
April 2016 in “Journal of Investigative Dermatology” This pilot study suggests that autophagy is crucial for anagen maintenance in human hair follicles, and targeting this process may help manage hair growth disorders.
February 2015 in “Dermatologic Surgery” This article discusses various affiliations of the authors with no reference to new research findings.
This study found that using Labrasol® in phospholipid vesicle formulations improved minoxidil's skin delivery and local accumulation, showing potential for treating hair growth disorders.
January 2012 in “TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES AEROSPACE TECHNOLOGY JAPAN” This paper outlines the research plan and current progress of a study analyzing mineral metabolism changes in astronauts by examining hair shafts after long-term space flight, with no new results yet.
March 2023 in “Epilepsia” This study suggests that repeated trilostane treatment increases brain allopregnanolone levels and delays epileptogenesis in rats after status epilepticus.
294 citations
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March 2016 in “European journal of cancer” This study found that neoadjuvant chemotherapy followed by interval debulking surgery led to better quality of life and lower perioperative morbidity compared to primary debulking surgery in advanced epithelial ovarian cancer patients with high tumor load.
236 citations
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April 2015 in “Cell” This study found that patterned hair plucking in mice triggers a collective regeneration response in nearby unplucked hair follicles via a quorum sensing mechanism involving immune signaling.
176 citations
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April 2011 in “Science” This study found that in a population of hair follicles, regenerative cycling stages are regulated by both intrinsic and extrinsic signals, with WNT/BMP signaling mediating interactions among follicles for adaptability.