11 citations
,
January 2020 in “Dermatologica Sinica” This study found that tofacitinib effectively promoted hair regrowth in Asian patients with severe alopecia areata, with 74.3% showing a clinical response.
10 citations
,
September 2015 in “PLoS ONE” This case report documents a female toddler with novel compound heterozygous mutations in the VDR gene causing hereditary 1,25-dihydroxyvitamin D-resistant rickets, expanding the known mutation spectrum for this disease.
10 citations
,
December 2011 in “Cell Transplantation” This study suggests that cultured human hair follicle cells can potentially recreate epidermis and produce bioengineered hair follicles in a GMP cell factory for regenerative therapy in alopecia.
9 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” This review discusses the role of tissue mechanics and extracellular matrix in skin aging processes and highlights potential therapeutic strategies, but reports no new clinical results.
9 citations
,
July 2020 in “Biomedicine & Pharmacotherapy” This study found that Pep-1-mediated mitochondrial transplantation was as effective as PRP therapy in restoring hair loss related to aging in mice, with distinct improvements in hair and skin-related measures.
9 citations
,
August 2018 in “JAAD Case Reports” This article discusses alopecia areata, highlighting its autoimmune nature and the lack of FDA-approved treatments, without providing new research findings.
8 citations
,
March 2020 in “Colloids and surfaces. B, Biointerfaces” This study suggests that extracting hair proteins at relatively high temperatures may enhance their hemostatic properties by altering their secondary structure and increasing the precipitation of soluble fibrinogen.
7 citations
,
June 2022 in “Biology” In this study, researchers observed that male COVID-19 patients with more than 23 CAG repeats in the androgen receptor gene and lower testosterone levels experienced more severe disease outcomes.
7 citations
,
July 2006 in “Journal of cutaneous pathology” This case report documents the first known instance of an ectopic sebaceous gland and duct within a hair follicle in a 21-year-old male with persistent acneiform eruption.
6 citations
,
June 2022 in “Journal of Orthopaedic Surgery and Research” In this animal study, oral administration of wedelolactone significantly improved bone mineral density and reduced osteoclast numbers in a model of particle-induced osteolysis, suggesting potential as a treatment option.
6 citations
,
March 2022 in “International journal of molecular sciences” This review explores the detrimental effects of sunlight on the skin’s circadian rhythm and photodamage, noting the potential of natural cosmeceuticals to influence this rhythm, but reports no new results.
5 citations
,
April 2021 in “Frontiers in Pharmacology” In this mouse study, the combination of minoxidil-coated lysozyme microbubbles and ultrasound significantly enhanced hair growth compared to minoxidil alone.
5 citations
,
February 2021 in “Gels” In this study, HYDRO DELUXE BIO was reported to show promise for scalp mesotherapy by enhancing angiogenesis and reducing inflammation in an in vitro model.
5 citations
,
January 2021 in “BioMed Research International” This study found that a noncrosslinked hyaluronic acid filler restored cell viability against UVB-induced cytotoxicity and increased VEGF secretion in human dermal papilla cells, suggesting potential for mesotherapy use after further research.
5 citations
,
January 2019 in “International Journal of STD & AIDS” This report discusses a rare case where immune reconstitution inflammatory syndrome in an HIV patient led to dermatologic, ophthalmologic, and neurologic complications due to secondary syphilis.
5 citations
,
November 2016 in “Experimental and Therapeutic Medicine” In this study, BeauTop treatment significantly increased hair growth in people with androgenetic alopecia compared to placebo, showing effectiveness without adverse reactions.
5 citations
,
February 2012 in “Aesthetic Plastic Surgery” This case report introduces a novel instance of long-term cutaneous neoplastic degeneration following artificial hair implantation, a previously unreported complication in such procedures.
4 citations
,
January 2025 in “Dermatologica Sinica” This consensus from the Taiwanese Dermatological Association suggests that for mild to moderate alopecia areata, first-line treatments may include topical or intralesional corticosteroids, possibly with topical minoxidil, while severe cases might require systemic corticosteroids or Janus kinase inhibitors.
4 citations
,
November 2020 in “Journal of the American Academy of Dermatology” This cohort study observed a bidirectional association between alopecia areata and migraine in Taiwanese patients, indicating that individuals with one condition have a higher risk of developing the other.
3 citations
,
February 2025 in “Endocrine” This study emphasizes the necessity of confirming elevated testosterone levels detected by immunoassay with liquid chromatography-tandem mass spectroscopy before pursuing more complex diagnostic evaluations.
3 citations
,
August 2022 in “International Journal of Molecular Sciences” This study demonstrated that 5-azacytidine treatment may reduce TSC lesion-related hair follicles in mice, suggesting chromatin remodeling agents could be effective for tuberous sclerosis cutaneous lesions lacking tuberin.
3 citations
,
May 2022 in “Journal of The American Academy of Dermatology” This source notes that while low-dose oral minoxidil is effective for treating androgenetic alopecia, it has been associated with electrocardiogram changes and palpitations even at low doses.
3 citations
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August 2021 in “Research Square (Research Square)” This study found that increased mRNA expression of the Ectodysplasin-A2-Receptor, observed across multiple species and tissues, may exacerbate inflammation during aging, suggesting potential benefits of blocking EDA2R/EDA-A2 signaling.
3 citations
,
May 2021 in “Dermatologic Clinics” This article reviews global insights on how COVID-19 has transformed the practice of dermatology, but it reports no new clinical results.
3 citations
,
January 2020
3 citations
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February 2018 in “InTech eBooks” This chapter discusses the current developments in Traditional Chinese Medicine for treating PCOS but reports no new clinical results, emphasizing the need for further research in this area.
2 citations
,
February 2024 in “International Journal of Molecular Sciences” This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.
2 citations
,
October 2023 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This case report found that dupilumab treatment in a 5-year-old with prurigo nodularis considerably reduced her itch severity and nearly cleared the skin lesions after six months.
2 citations
,
May 2021 in “Scientific Reports” In this study, researchers found that stress likely triggers symmetrical alopecia in Formosan macaques in Mt. Longevity, Taiwan, with higher stress hormone levels associated with the condition.
2 citations
,
June 2012 in “Dermatologica Sinica” Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.