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This review discusses the incidence, reversibility, and impact of chemotherapy-induced alopecia and concludes that scalp cooling is the most effective prevention method in most cases, though some questions remain.

In this rat study, subcutaneous injections of hydrogen peroxide and cumene hydroperoxide appeared to completely prevent chemotherapy-induced hair loss by inducing cell cycle arrest, suggesting a novel approach to help cancer patients maintain their quality of life during treatment.

This study found that the computer-controlled RV-01 scalp cooling device helped prevent significant hair loss in metastatic breast cancer patients treated with eribulin, with none of the 16 patients requiring a wig and experiencing minimal discomfort.

This study suggests that chemotherapy-induced anagen effluvium represents patterned hair loss, with most patients retaining hairlines, but patterns do not vary significantly by age, symptoms, or chemotherapy type.

This review explores the possibility of using the side effects of chemotherapeutic agents for regenerating hair follicles, potentially offering a new treatment avenue for different types of alopecia.

In this study, researchers observed diffuse hair loss in Japanese patients post-hematopoietic stem cell transplantation and chemotherapy, with treatments targeting hair follicle miniaturization, like topical minoxidil, improving hair volume in about 52.9% of cases.

This review discusses the pathobiology of chemotherapy-induced alopecia and highlights challenges in managing it, reporting no new clinical results and emphasizing the need for well-designed preclinical models to develop effective treatments.

This study suggests that targeting the activation of transit-amplifying cell-derived progenitor cells may help prevent hair loss from chemotherapy and radiotherapy by promoting hair follicle regeneration.

In this study, researchers reported that the activation of EDA2R by p53 leads to p53-dependent cell death in cancer cells and is involved in chemotherapy-induced hair loss.

This study reports that mesenchymal stromal cell-derived extracellular vesicle injections led to complete hair regrowth in a patient with persistent chemotherapy-induced alopecia.

This review discusses chemotherapy-induced hair loss, highlighting that topical minoxidil can lessen its severity or duration but not prevent it, and reports no new clinical results.

This study reports that hair follicles can mobilize ectopic progenitors for regeneration to repair damage from ionizing radiation. Augmenting WNT signaling enhanced this regenerative process and prevented radiation- and chemotherapy-induced hair loss, highlighting a potential approach to manage alopecia during cancer treatment.

This article reviews recent research and advancements in scalp cooling for preventing chemotherapy-induced hair loss, reporting no new clinical results.

This article explores the potential of combining biomarkers to assess and improve treatments for chemotherapy-induced alopecia, highlighting the limited availability of data on hair follicle damage markers with and without scalp cooling.

This study found that human scalp hair follicles transplanted onto chemotherapy-treated immunodeficient mice closely mimic chemotherapy-induced hair loss seen in cancer patients, providing a valuable model for research.

This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.

Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.

This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.

In this study, researchers found that chemotherapy-induced alopecia counseling and resource access are insufficient and influenced by socioeconomic factors such as employment, income, and education, underscoring the need for standardized education and improved resource availability to address disparities.

This paper examines the development of scalp cooling as a non-drug method to reduce chemotherapy-induced hair loss, addressing an emotionally challenging side effect of cancer treatment. Results are not provided in the abstract.

In this descriptive study conducted in a tertiary care center in Chennai, researchers observed that chemotherapy-induced hair loss seriously impacts the emotional well-being of cancer survivors, especially women and younger individuals, with severity of hair loss correlating strongly with psychological distress.

In this study, scalp cooling therapy was found to be well tolerated and effective at improving hair preservation for Asian women with breast or gynecological cancers undergoing certain chemotherapy regimens, particularly weekly paclitaxel, compared to historical controls.

This study will investigate the efficacy of YH0618 granules on reducing chemotherapy-induced hair loss in breast cancer patients, focusing on potential mechanisms related to kidney deficiency, with outcomes not yet reported.

This study aims to evaluate the efficacy of the traditional Chinese medicine YH0618 granule for reducing chemotherapy-induced hair loss in breast cancer patients through a double-blind, randomized clinical trial, assessing hair loss progression and improving quality of life markers compared to a placebo.

This study aims to assess the effectiveness of the YH0618 granule in reducing chemotherapy-induced hair loss in breast cancer patients, without disrupting anti-tumor effects, by conducting a randomized, double-blind trial. Results are not reported in the abstract.

In this study, researchers will conduct a randomized, double-blind, multi-center clinical trial to assess the effectiveness of YH0618 granule in preventing chemotherapy-induced hair loss among breast cancer patients, aiming to understand its mechanism related to kidney deficiency in Chinese Medicine. Results are not yet reported.

The conclusion is unclear about minoxidil's effectiveness for preventing hair loss from chemotherapy.

This study found that nearly 40% of Hodgkin’s Lymphoma patients who received Brentuximab Vedotin with AVD chemotherapy experienced persistent alopecia more than two years after treatment, leading to significant psychosocial consequences such as reduced self-confidence and emotional distress.

In this study, various cellular responses and signaling pathways were examined in hair follicles after exposure to ionizing radiation, including the effects of Wnt3a treatment, with findings noted in apoptosis, DNA damage, and differentiation processes.

Results are not reported in this study, which investigated the effects of radiation on hair follicles and evaluated various cellular responses and signaling pathways, particularly focusing on WNT signaling and the impact of Wnt3a treatment.