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CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Tadalafil and Finasteride may help treat aggressive melanoma.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

New therapies are being developed that target integrin pathways to treat various diseases.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Activating Nrf2 can help protect against hearing loss.

Kang-ai injection with platinum-based chemotherapy improves tumor response and immune function while reducing side effects in advanced lung cancer.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Stem cells and their exosomes show promise for repairing tissues and healing wounds when delivered effectively, but more research is needed on their tracking and optimal use.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Mild oxidative stress can prevent hair loss from chemotherapy.

Skin cancer often starts from Lgr5+ progenitor cells.

Different types of skin fibroblasts have unique roles in skin health and disease.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

Targeting lipid metabolism can help treat advanced, resistant cancers.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.