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The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Supercritical CO2 extraction makes rice bran oil healthier and safer than traditional methods.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Leucaena leucocephala is nutritious but needs careful processing to remove toxins.

Finasteride delivery through skin improved using invasomes and iontophoresis.

The Cell Membrane Complex in hair has both water-attracting and water-repelling layers.

Melanin density affects hair color, and this method can help in cosmetic assessments and diagnosing hair diseases.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Different scalp imaging methods are important for studying hair and scalp health and require more volunteers for better evaluation.

Finasteride may affect PNMT, causing side effects.

Microbial communities in Duku plant roots vary between wet and dry habitats, affecting plant health.

Zinc is essential for plant growth and human health, but many soils lack enough zinc, affecting crops and potentially leading to health problems.

Anti-glycation treatments might slow skin aging, but more research is needed.

Acidic sandy clay damages archaeological hair the most, while dry conditions preserve but make it brittle; silicone oil can help keep the hair flexible.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Liposomes better deliver minoxidil for hair loss treatment than niosomes.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

Cosmetic treatments like bleaching and perming can greatly reduce opiate levels in hair, possibly leading to false-negative drug tests.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.